A NOVEL ORGANOTYPIC CORTICAL SLICE CULTURE MODEL FOR TRAUMATIC BRAIN INJURY: MOLECULAR CHANGES INDUCED BY INJURY AND MESENCHYMAL STROMAL CELL SECRETOME TREATMENT

Traumatic brain injury (TBI) is a major worldwide neurological disorder with no neuroprotective treatment available.Three-dimensional (3D) in vitro models of brain contusion serving as a screening platform for drug testing are lacking.Here we developed a new in vitro model of brain contusion on organotypic cortical brain slices and tested its respo

A multiyear study was conducted to determine if soil amendment combined with topical application of elemental sulfur could be employed to reduce deer browse damage to four conifer species.Fertilizer and sulfur were applied to conifer seedlings at seven sites near Corvallis, OR.Growth and browse damage data were collected for all seedlings over a pe

Many cities in Mexico experience recurrent floods, caused by changes in land use, the modification of surface and land runoff, the artificialization of areas initially intended for infiltration and recharge of groundwater and, in general, the insufficiency and deficiency of the local networks of urban drainage, incapable to evacuate the annual surp